900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinônimo(s): Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• Fórmula empírica (Notação de Hill): C₁₁H₁₂BrFO₂SSi
• Número CAS: 2088829-15-4
• Peso molecular: 335.26
• Código UNSPSC: 12352200
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95%
• forma: powder or crystals
• adequação da reação: reaction type: click chemistry
• temperatura de armazenamento: −20°C

Descrição

Aplicação

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable