900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

• Sinônimo(s): Carboxyl diazirine alkyne, Probe building block
• Fórmula empírica (Notação de Hill): C₈H₁₀N₂O₂
• Número CAS: 1450754-37-6
• Peso molecular: 166.18
• Número MDL: MFCD31433997
• Código UNSPSC: 12352106

Propriedades

• Formulário: liquid
• Nível de qualidade: 100
• adequação da reação: reaction type: click chemistry
• disponibilidade: available only in USA
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C#CCCC1(N=N1)CCC(O)=O
• InChI: 1S/C8H10N2O2/c1-2-3-5-8(9-10-8)6-4-7(11)12/h1H,3-6H2,(H,11,12)
• chave InChI: JRNSKSYASHYNCM-UHFFFAOYSA-N

Descrição

Aplicação

Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein

Technology Spotlight: Trifuctional Probe Building Blocks

Informações de segurança

• Pictogramas: GHS02
• Palavra indicadora: Danger
• Frases de perigo: H242
• Declarações de precaução: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classificações de perigo: Self-react. C
• Código de classe de armazenamento: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable