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900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

Sinônimo(s):

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

Fórmula empírica (Notação de Hill):
C14H15F3N2OSi
Número CAS:
2187374-13-4
Peso molecular:
312.36
Código UNSPSC:
12352200
NACRES:
NA.22

Ensaio

≥95%

Formulário

powder or crystals

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Aplicação

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas

Technology Spotlight: Trifunctional Probe Building Blocks

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone ≥95%

Sigma-Aldrich

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

Artigos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Global Trade Item Number

SKUGTIN
900862-25MG4061833251287

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