900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

• Sinônimo(s): Amino sulfonyl fluoride TMS-alkyne, Probe building block
• Fórmula empírica (Notação de Hill): C₁₁H₁₄FNO₂SSi
• Número CAS: 2088828-95-7
• Peso molecular: 271.38
• Código UNSPSC: 12352200
• NACRES: NA.22

Propriedades

• Formulário: liquid
• disponibilidade: available only in USA
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: NC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

Descrição

Aplicação

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informações de segurança

• Pictogramas: GHS02
• Palavra indicadora: Danger
• Frases de perigo: H242
• Declarações de precaução: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classificações de perigo: Self-react. C
• Código de classe de armazenamento: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable