850725P

18:1 (Δ9-Cis) PE (DOPE)

Avanti Research^™ - A Croda Brand

• Synonim(y): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; DOPE; PE(18:1(9Z)/18:1(9Z)); 110635, DOPE
• Wzór empiryczny (zapis Hilla): C₄₁H₇₈NO₈P
• Numer CAS: 4004-05-1
• Masa cząsteczkowa: 744.03
• Kod UNSPSC: 51191904
• NACRES: NA.25

Właściwości

• opis: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
• Próba: >99% (TLC)
• Postać: powder
• opakowanie: pkg of 1 × 1 g (850725P-1g); pkg of 2 × 100 mg (850725P-200mg); pkg of 5 × 100 mg (850725P-500mg); pkg of 1 × 25 mg (850725P-25mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand
• Zastosowanie: advanced drug delivery
• typ lipidu: cardiolipins; phospholipids
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
• InChI: 1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1
• Klucz InChI: MWRBNPKJOOWZPW-NYVOMTAGSA-N

Opis

Opis ogólny

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (18:1 (Δ9-Cis) PE (DOPE)) is a neutral phospholipid and displays sensitivity towards pH change. At acidic it is an inverted hexagonal micelle and transforms to spherical micelle at alkaline pH.

Zastosowanie

18:1 (Δ9-Cis) PE (DOPE) has been used in the preparation of liposome for human uncoupling protein 1 (UCP1) reconstitution and for Caenorhabditis elegans autophagy related cysteine protease protein conjugation studies. It has also been used for the generation of giant unilamellar vesicles (GUVs) for septin induced deformation studies.

Działania biochem./fizjol.

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (18:1 (Δ9-Cis) PE (DOPE)) forms a stable lipid layer and rapidly fuses with endosomal lipid bilayer. DOPE in combination with 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) has high in vitro transfection efficiency.

Opakowanie

20 mL Clear Glass Screw Cap Vial (850725P-1g)

5 mL Clear Glass Sealed Ampule (850725P-200mg)

5 mL Clear Glass Sealed Ampule (850725P-25mg)

5 mL Clear Glass Sealed Ampule (850725P-500mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable