700001P

DC-Cholesterol HCl

Avanti Research^™ - A Croda Brand 700001P, powder

• Synonim(y): 3β-[N-(N′,N′-dimethylaminoethane)-carbamoyl]cholesterol hydrochloride
• Wzór empiryczny (zapis Hilla): C₃₂H₅₇N₂O₂Cl
• Numer CAS: 166023-21-8
• Masa cząsteczkowa: 537.26
• Kod UNSPSC: 12352211
• NACRES: NA.25

Właściwości

• Próba: >99% (TLC)
• Formularz: powder
• opakowanie: pkg of 1 × 1 g (700001P-1g); pkg of 1 × 200 mg (700001P-200mg); pkg of 1 × 25 mg (700001P-25mg); pkg of 1 × 500 mg (700001P-500mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand 700001P
• Zastosowanie: vaccine development
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [H][C@](C1)(OC(NCC[N+](C)([H])C)=O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](C)CCCC(C)C.[Cl-]
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H
• Klucz InChI: ISXSJGHXHUZXNF-UHFFFAOYSA-N

Opis

Opis ogólny

DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.

DC-Cholesterol HCl is a sterol-based transfection reagent.

Zastosowanie

DC-Cholesterol HCl is suitable:

• for the preparation of ultrasound cationic microbubbles
• to prepare liposomes
• for the preparation of L-glutathione (GSH), loaded proliposomes

DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.

Działania biochem./fizjol.

DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).

DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.

Opakowanie

20 mL Clear Glass Screw Cap Vial (700001P-1g)

20 mL Clear Glass Screw Cap Vial (700001P-500mg)

5 mL Amber Glass Screw Cap Vial (700001P-200mg)

5 mL Amber Glass Screw Cap Vial (700001P-25mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable