860516P

C16 Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand

• Synonim(y): N-palmitoyl-D-erythro-sphingosine
• Wzór empiryczny (zapis Hilla): C₃₄H₆₇NO₃
• Numer CAS: 24696-26-2
• Masa cząsteczkowa: 537.90
• Numer MDL: MFCD00871748
• Kod UNSPSC: 12352211
• NACRES: NA.25

Właściwości

• Formularz: powder
• opakowanie: pkg of 1 × 10 mg (860516P-10mg); pkg of 1 × 100 mg (860516P-100mg); pkg of 1 × 25 mg (860516P-25mg); pkg of 1 × 5 mg (860516P-5mg); pkg of 1 × 50 mg (860516P-50mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand
• typ lipidu: sphingolipids
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1
• Klucz InChI: YDNKGFDKKRUKPY-TURZORIXSA-N

Opis

Opis ogólny

Ceramide comprise sphingosine and fatty acid and belongs to the sphingolipids family.

Zastosowanie

C16 Ceramide (d18:1/16:0) has been used:

• as an internal standard in the chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry for myocardial ceramide quantification
• as an internal standard for the ceramide quantification from rat samples using liquid chromatography-mass spectrometry
• to test its effect on mitochondrial stress response in worms

Działania biochem./fizjol.

C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In general, ceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53.

Opakowanie

5 mL Amber Glass Screw Cap Vial (860516P-100mg)

5 mL Amber Glass Screw Cap Vial (860516P-10mg)

5 mL Amber Glass Screw Cap Vial (860516P-25mg)

5 mL Amber Glass Screw Cap Vial (860516P-50mg)

5 mL Amber Glass Screw Cap Vial (860516P-5mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable