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860512P

Avanti

C12 Ceramide (d18:1/12:0)

Avanti Research - A Croda Brand

Synonim(y):

N-lauroyl-D-erythro-sphingosine

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About This Item

Wzór empiryczny (zapis Hilla):
C30H59NO3
Numer CAS:
Masa cząsteczkowa:
481.79
Numer MDL:
Kod UNSPSC:
12352211
NACRES:
NA.25

Formularz

powder

opakowanie

pkg of 1 × 10 mg (860512P-10mg)
pkg of 1 × 25 mg (860512P-25mg)
pkg of 1 × 5 mg (860512P-5mg)

producent / nazwa handlowa

Avanti Research - A Croda Brand

typ lipidu

sphingolipids

Warunki transportu

dry ice

temp. przechowywania

−20°C

ciąg SMILES

OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1

Klucz InChI

HXFPPRPLRSPNIB-VARSQMIESA-N

Opis ogólny

C12 Ceramide (d18:1/12:0) is a synthetic ceramide containing sphingosine with lauric acid.

Zastosowanie

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:
  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for lipid extraction in U87MG (human glioma cell line)
  • as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues

Działania biochem./fizjol.

Ceramides are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

Opakowanie

5 mL Amber Glass Screw Cap Vial (860512P-10mg)
5 mL Amber Glass Screw Cap Vial (860512P-25mg)
5 mL Amber Glass Screw Cap Vial (860512P-5mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
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Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main
Megan Melland-Smith et al.
Autophagy, 11(4), 653-669 (2015-04-09)
Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological processes by regulating cell death and survival. The objective of the current study was to examine ceramide metabolism in preeclampsia, a serious disorder of pregnancy characterized by oxidative stress

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