911690

C5 Lenalidomide

≥95%

• 別名: 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC^® research
• 実験式（ヒル表記法）: C₁₃H₁₃N₃O₃
• CAS番号: 191732-70-4
• 分子量: 259.26
• MDL番号: MFCD31692701
• UNSPSCコード: 12352101
• NACRES: NA.22

特性

• ligand: C5 Lenalidomide
• 品質水準: 100
• アッセイ: ≥95%
• 形状: powder
• 反応適合性: reagent type: ligand
• 保管温度: 2-8°C
• SMILES記法: NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

詳細

アプリケーション

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

その他情報

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

Targeted Protein Degradation by Small Molecules

法的情報

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Warning
• 危険有害性情報: H361d,H373
• 注意書き: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 2 - STOT RE 2
• ターゲットの組織: Blood
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable