29208

(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide

for protein sequence analysis (by MALDI-MS), ≥98.5%

• Synonim(y): N-Succinimidyl [tris(2,4,6-trimethoxyphenyl)phosphonio]acetate bromide, TMPP-Ac-OSu
• Wzór empiryczny (zapis Hilla): C₃₃H₃₉BrNO₁₃P
• Numer CAS: 226409-58-1
• Masa cząsteczkowa: 768.54
• Numer MDL: MFCD03095505
• Kod UNSPSC: 41116105
• Identyfikator substancji w PubChem: 329753320
• NACRES: NA.21

Właściwości

• klasa czystości: for protein sequence analysis (by MALDI-MS)
• Poziom jakości: 100
• Próba: ≥98.5% (HPLC); ≥98.5%
• metody: MALDI-MS: suitable
• mp: 199-205 °C (dec.)
• temp. przechowywania: −20°C
• ciąg SMILES: [Br-].COc1cc(OC)c(c(OC)c1)[P+](CC(=O)ON2C(=O)CCC2=O)(c3c(OC)cc(OC)cc3OC)c4c(OC)cc(OC)cc4OC
• InChI: 1S/C33H39NO13P.BrH/c1-38-19-12-22(41-4)31(23(13-19)42-5)48(18-30(37)47-34-28(35)10-11-29(34)36,32-24(43-6)14-20(39-2)15-25(32)44-7)33-26(45-8)16-21(40-3)17-27(33)46-9;/h12-17H,10-11,18H2,1-9H3;1H/q+1;/p-1
• Klucz InChI: YKMSQZIYVKTUHI-UHFFFAOYSA-M

Opis

Opis ogólny

N-Succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP-Ac-OSu) is an acylating reagent, and is generally used for the selective derivatization of N-terminal a-amino group of peptide. The TMPP-acetylated peptides undergo fragmentation thereby creating a-type ions, thus obtaining sequence information becomes easier, even without the usage of automated computational approach. It can be used as a labelling reagent in liquid chromatography-coupled mass spectrometry (LC-MS/MS) of N-terminal peptides, so as to improve ionization efficiency, simplify fragmentation, and retention times, thereby leading to better separation of peptides.

Zastosowanie

TMPP-Ac-OSu was used for labelling peptides, in tandem mass spectrometry, done for converting arginine to ornithine, in order to improve the fragmentation pattern of peptides.

Opakowanie

Bottomless glass bottle. Contents are inside inserted fused cone.

Inne uwagi

Reagent for modifying N-termial of peptides for fast atom bombardment, FAB or matrix assisted laser desorption/ionization MS, MALDI MS

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)