Przejdź do zawartości
Merck
Wszystkie zdjęcia(1)

Dokumenty

70990

Supelco

α-Cyano-4-hydroxycinnamic acid

matrix substance for MALDI-MS, ≥99.0% (HPLC)

Synonim(y):

α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wszystkie zdjęcia(1)

About This Item

Wzór liniowy:
HOC6H4CH=C(CN)CO2H
Numer CAS:
28166-41-8
Masa cząsteczkowa:
189.17
Beilstein:
3271427
Numer WE:
248-879-1
Numer MDL:
MFCD00004204
Kod UNSPSC:
12000000
Identyfikator substancji w PubChem:
329762519
NACRES:
NA.21

klasa czystości

matrix substance for MALDI-MS

Poziom jakości

100

Próba

≥99.0% (HPLC)

Postać

solid

klasy chemiczne analitów

glycans, peptides, proteins

metody

MALDI-MS: suitable

mp

245-250 °C (lit.)
245-250 °C

rozpuszczalność

methanol: 10 mg/mL, clear

ślady kationów

Ba: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
K: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤10 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

absorpcja

≥2000 at 337 nm (mol. absorption)

ciąg SMILES

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

Klucz InChI

AFVLVVWMAFSXCK-VMPITWQZSA-N

Szukasz podobnych produktów? Odwiedź Przewodnik dotyczący porównywania produktów

Powiązane kategorie

Opis ogólny

α-Cyano-4-hydroxycinnamic acid (α-CHCA) is widely used as a matrix in order to facilitate ionization of peptides and proteins in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer.

Zastosowanie

α-CHCA was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF.

Inne uwagi

Matrix substance used in MALDI-MS (matrix-assisted laser desorption ionization MS) peptide analysis in proteomics.
This page may contain text that has been machine translated.

produkt powiązany

Numer produktu
Opis
Cennik

P2613

ProteoMass™ P14R MALDI-MS Standard, vial of 10 nmol

C8857

ProteoMass™ Cytochrome c MALDI-MS Standard, vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

A8346

ProteoMass™ ACTH Fragment 18-39 MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 2,464.1989 Da

I6154

ProteoMass™ Insulin chain B oxidized MALDI-MS Standard, vial of 10 nmol

I6279

ProteoMass™ Insulin MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 5,729.6087 Da

A8471

ProteoMass™ Albumin MALDI-MS Standard, vial of 10 nmol, average mol wt 66,429.09 Da by calculation

A9096

ProteoMass™ Aldolase MALDI-MS Standard, vial of 10 nmol, average mol wt 39,211.28 Da by calculation

A8846

ProteoMass™ Angiotensin II MALDI-MS Standard, vial of 10 nmol

A8971

ProteoMass™ Apomyoglobin MALDI-MS Standard, vial of 10 nmol, (M+H+) 16,952.27 Da by calculation

B4181

ProteoMass™ Bradykinin Fragment 1-7 MALDI-MS Standard, vial of 10 nmol, monoisotopic mol wt 756.3997 Da

MSCAL1

ProteoMass™ Peptide and Protein MALDI-MS Calibration Kit, Peptide and Protein MALDI MS Calibration Standard

MSCAL2

ProteoMass™ Peptide MALDI-MS Calibration Kit, Peptide MALDI MS Calibration Standard

MSCAL3

ProteoMass™ Protein MALDI-MS Calibration Kit, Protein MALDI MS Calibration Standard

56197

3-Hydroxypicolinic acid, matrix substance for MALDI-MS, ≥99.0% (HPLC)

54793

2-(4-Hydroxyphenylazo)benzoic acid, matrix substance for MALDI-MS, ≥99.5%

85429

Sinapic acid, matrix substance for MALDI-MS, ≥99.0% (T)

03565

MALDI validation set polystyrene Mp ~700 - 70 000, certified reference material

37468

2′,6′-Dihydroxyacetophenone, matrix substance for MALDI-MS, ≥99.5%

91928

2′,4′,6′-Trihydroxyacetophenone monohydrate, matrix substance for MALDI-MS, ≥99.5%

03597

MALDI validation set PS, PMMA, PDMS, PEG and PSS Mp ~4′300 - 6′500

87884

trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile, matrix substance for MALDI-MS, ≥99.0% (HPLC)

60018

Caffeic acid, matrix substance for MALDI-MS, ≥99.0% (HPLC)

29208

(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide, for protein sequence analysis (by MALDI-MS), ≥98.5%

46278

trans-Ferulic acid, matrix substance for MALDI-MS, ≥99.0% (HPLC)

85707

2,5-Dihydroxybenzoic acid, matrix substance for MALDI-MS, >99.0% (HPLC)

N3786

α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens, Proteomics Grade, suitable for MALDI-TOF MS

39468

α-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, Ultra pure

49508

Sinapic acid, matrix substance for MALDI-MS, ≥99.5%, Ultra pure

50862

Super-DHB, suitable for matrix substance for MALDI-MS, ≥99.0%

02241

2′,3′-Dideoxycytidine 5′-triphosphate sodium salt solution, suitable for MALDI-MS, ≥98.0% (HPLC)

42597

3′-Deoxythymidine 5′-triphosphate sodium salt solution, BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)

MS0100

ProteoMass™ Guanidination Kit, For improving MALDI-MS sensitivity and peptide sequence coverage

MSCAL4

ProteoMass™ MALDI Calibration Kit for Exactive Series MS, LTQ XL and LTQ Hybrids, MALDI MS Calibration Standard

92817

9-Aminoacridine, matrix substance for MALDI-MS, ≥99.5% (HPLC)

56451

1,5-Diaminonaphthalene, matrix substance for MALDI-MS, ≥99.0% (HPLC)

50757

Micro-Array for Mass Spectrometry (MAMS), for single cell analysis

94141

4-Chloro-α-cyanocinnamic acid, matrix substance for MALDI-MS, ≥95.0% (HPLC)

89063

4-Bromo-α-cyanocinnamic acid, matrix substance for MALDI-MS, ≥95.0% (HPLC)

77081

α-Cyano-4-fluorocinnamic acid, matrix substance for MALDI-MS, ≥95.0% (HPLC)

38419

α-Cyano-2,3,4,5,6-pentafluorocinnamic acid, matrix substance for MALDI-MS, ≥95.0% (HPLC)

39379

4-Chloro-α-cyanocinnamic acid - α-Cyano-2,4-difluorocinnamic acid mixture, matrix substance for MALDI-MS, ≥95.0% (sum of both components, HPLC)

68914

4-Bromo-α-cyanocinnamic acid - 4-Chloro-α-cyanocinnamic acid mixture, matrix substance for MALDI-MS, ≥95.0% (sum of both components, HPLC)

05851

4-Aminoquinaldine, matrix substance for MALDI-MS, ≥99.0% (HPLC)

78246

Curcumin, matrix substance for MALDI-MS, ≥99.5% (HPLC)

04973

Micro-Array for Mass Spectrometry (MAMS), for quantitative MALDI

94477

(E)-2-Cyano-3-(2-naphthyl)acrylic acid, matrix substance for MALDI-MS, ≥98.0% (HPLC)

83788

(2E)-3-(9-Anthryl)-2-cyanoacrylic acid, matrix substance for MALDI-MS, ≥97.0% (HPLC)

76884

Anthranilamide, matrix substance for MALDI-MS, ≥99.0% (HPLC)

56229

9-Nitroanthracene, matrix substance for MALDI-MS, ≥98.5% (HPLC)

PFS11

SpheriCal™ Mix, Peptide Low, suitable for MALDI-MS

PFS31

SpheriCal™ Aqua, Peptide Medium, suitable for MALDI-MS

PFS32

SpheriCal™ Aqua, Peptide High, suitable for MALDI-MS

PFS20

SpheriCal™ Neat, Peptide Low, suitable for MALDI-MS

PFS21

SpheriCal™ Neat, Peptide Medium, suitable for MALDI-MS

PFS22

SpheriCal™ Neat, Peptide High, suitable for MALDI-MS

PFS23

SpheriCal™ Neat, Protein Low, suitable for MALDI-MS

PFS30

SpheriCal™ Aqua, Peptide Low, suitable for MALDI-MS

69028

4-Phenyl-α-cyanocinnamamide, matrix substance for MALDI-MS, ≥98.5% (HPLC)

900666

Bruker standard solvent, suitable for MALDI-MS, 50% ACN + 47.5% H2O + 2.5% TFA

Piktogramy

Exclamation mark
GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H317

Zwroty wskazujące środki ostrożności

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Klasyfikacja zagrożeń

Skin Sens. 1B

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certyfikaty analizy (CoA)

Lot/Batch Number
BCCG3811
BCCC8081
BCBZ5249
BCBV7481
BCBQ6945V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

S.D. Patterson, V. Katta
Analytical Chemistry, 66, 3729-3729 (1994)
J Gobom et al.
Analytical chemistry, 73(3), 434-438 (2001-02-24)
We present a new MALD1 sample preparation technique for peptide analysis using the matrix alpha-cyano-4-hydroxy-cinnamic acid (CHCA) and prestructured sample supports. The preparation integrates sample purification, based on the affinity of microcrystalline CHCA for peptides, thereby simplifying the analysis of
Xiangping Zhu et al.
Journal of biomolecular techniques : JBT, 14(4), 298-307 (2004-01-13)
Alpha-cyano-4-hydroxycinnamic acid (alpha-CHCA) as a matrix facilitates the ionization of proteins and peptides in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer. The matrix itself also ionizes and so do its sodium and potassium adducts. Matrix clusters and metal
Martin Winter et al.
SLAS discovery : advancing life sciences R & D, 24(7), 766-777 (2019-05-07)
Microbial-dependent trimethylamine (TMA) generation from dietary precursors such as choline was recently linked to cardiovascular diseases (CVDs) as well as chronic kidney disease (CKD). Inhibition of TMA-generating enzymes in gut bacteria would be an innovative approach to treat these diseases.
Kevser Biberoglu et al.
Biochimica et biophysica acta, 1834(4), 745-753 (2013-01-29)
Acetylcholinesterase (AChE) in the serum of fetal cow is a tetramer. The related enzyme, butyrylcholinesterase (BChE), in the sera of humans and horse requires polyproline peptides for assembly into tetramers. Our goal was to determine whether soluble tetrameric AChE includes
Wyświetl wszystkie powiązane dokumenty

Powiązane treści

Analiza masy przeciwciał monoklonalnych w stanie nienaruszonym

Odkryj naszą szeroką gamę produktów do analizy masy przeciwciał monoklonalnych w stanie nienaruszonym, w tym kolumny wykluczające (SEC), kolumny jonowymienne, kolumny fazy odwróconej, bufory HPLC, matryce i wzorce MALDI, rozpuszczalniki o wysokiej czystości, odczynniki, narzędzia do przygotowywania próbek białek i certyfikowane materiały referencyjne.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej