ESR1

estrogen receptor 1

Sinônimos:

ER, ESR, ESRA, ESTRR, Era, NR3A1

Espécies:

Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), Goat ESR1 (100860768), sheep ESR1 (443228), domestic guinea pig Esr1 (100713276), Zebrafish esr1 (259252), dog ESR1 (403640), cow ESR1 (407238), Horse ESR1 (791249) ...Mais

ID UniProtKB:

P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7

ID do gene:

Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Mouse(13982) estrogen receptor 1 (alpha)
Rat(24890) estrogen receptor 1
Goat(100860768) estrogen receptor 1
sheep(443228) estrogen receptor 1
domestic guinea pig(100713276) estrogen receptor 1
Zebrafish(259252) estrogen receptor 1
dog(403640) estrogen receptor 1
cow(407238) estrogen receptor 1
Horse(791249) estrogen receptor 1
domestic cat(552888) estrogen receptor 1
chicken(396099) estrogen receptor 1
Thale Cress(837856) ethylene-responsive transcription factor ESR1

Produtos (182)
Artigos revisados por pares (901)

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Small Molecule - Activator

Número do produto

Descrição

Espécies

131083

4-Phenylazophenol, 98%,

Espécies

human

N0632

ββ-Dinucleotídeo de nicotinamida adenina, ,

Espécies

human

139939

trans-Stilbene, 96%,

Espécies

human, rat

43410

β-Dinucleotídeo de nicotinamida adenina, ≥95% (HPLC),

Espécies

human

S4808

cis-Stilbene, 96%,

Espécies

human, rat

Small Molecule - Agonist

Número do produto

Descrição

Espécies

E-060

17β-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®,

Espécies

human

E-075

Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®,

Espécies

human

855871

Mestranol, 99%,

Espécies

human

E8004

β-Estradiol 17-cypionate, ,

Espécies

human

H6036

1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole, powder, ≥98% (HPLC),

Espécies

human

Small Molecule - Allosteric Modulator

Número do produto

Descrição

Espécies

85256

Tamoxifeno, analytical standard,

Espécies

human

BP1225

Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,

Espécies

human

06734

Tamoxifeno, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,

Espécies

human

T0014000

Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,

Espécies

human

T0015000

Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard,

Espécies

human

Small Molecule - Antagonist

Número do produto

Descrição

Espécies

524980

Dibutyl phthalate, 99%,

Espécies

mouse

308501

Benzyl butyl phthalate, 98%,

Espécies

mouse

Z2125

Zearalenone, fungal mycotoxin,

Espécies

mouse

290823

4-tert-Octylphenol, 97%,

Espécies

mouse

49085

Atrazine, analytical standard,

Espécies

mouse

Antibodies

Número do produto

Descrição

Reatividade de espécies

Aplicação

SAB4500813

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Reatividade de espécies

human

Aplicação

ELISA
immunohistochemistry
western blot

HPA000449

Anti-ESR1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Reatividade de espécies

human

Aplicação

immunofluorescence
immunohistochemistry
western blot

04-1564

Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,

Reatividade de espécies

human, mouse, rat

Aplicação

immunocytochemistry
western blot

07-662

Anti-Estrogen-related Receptor α Antibody, Upstate^®, from rabbit,