43410

β-Dinucleotídeo de nicotinamida adenina

≥95% (HPLC)

• Sinônimo(s): β-DPN, β-NAD, Coenzima 1, Cozimase, DPN, NAD, Nadide, Nucleotídeo de difosfopiridina
• Fórmula empírica (Notação de Hill): C₂₁H₂₇N₇O₁₄P₂ · xH₂O
• Número CAS: 53-84-9
• Peso molecular: 663.43 (anhydrous basis)
• Número CE: 200-184-4
• Número MDL: MFCD00036253
• Código UNSPSC: 12352111
• eCl@ss: 39200202
• ID de substância PubChem: 57650177
• NACRES: NA.55

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: powder or crystals
• Impurezas: ≤4% water
• cor: white to faint yellow
• solubilidade: H₂O: 0.1 g/mL at 20 °C, clear; H₂O: freely soluble
• traços de cátion: Ca: ≤200 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cr: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; K: ≤50 mg/kg; Mg: ≤100 mg/kg; Mn: ≤50 mg/kg; Na: ≤1000 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• razão de absorbância: A_{280/260 nm} 0.22 ±0.02; A_{250/260 nm} 0.83 ±0.03
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• chave InChI: BAWFJGJZGIEFAR-NNYOXOHSSA-N
• Informações sobre genes: human ... ESR1(2099) , ESR2(2100)

Descrição

Aplicação

β-Nicotinamide adenine dinucleotide hydrate has been used as a component of fibroblast cell culture media. It has also been used to study the viability of the cartilage constructs.

β-Nicotinamide adenine dinucleotide hydrate was used as a test compound for studying the structure and electrochemical properties of NADH electrocatalysts.

Ações bioquímicas/fisiológicas

Aceptor de elétrons

β-Nicotinamide adenine dinucleotide is a cofactor for alcohol dehydrogenase that serves as inhibitory neurotransmitter in visceral smooth muscle.

β-nicotinamide adenine dinucleotide (β-NAD) is a coenzyme present in most living cells. It is implicated in redox reactions and posttranslational modifications. β-NAD also acts as a substrate for various enzymes in several cellular processes.

Embalagem

Embalado com base no peso sólido.

Outras notas

Esta é a forma comum da NAD.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)