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900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

Sinonimo/i:

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

Formula empirica (notazione di Hill):
C14H15F3N2OSi
Numero CAS:
2187374-13-4
Peso molecolare:
312.36
Codice UNSPSC:
12352200
NACRES:
NA.22

Saggio

≥95%

Stato

powder or crystals

Temperatura di conservazione

−20°C

Stringa SMILE

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Applicazioni

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifunctional Probe Building Blocks

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

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(4-(Aminomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, 95%

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900611

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900610

Hydroxyl di-benzophenone (PEG)3 alkyne

900617

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900619

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900618

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900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, ≥95%

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900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

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3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900863

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900864

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900865

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907308

(3-(1,1-Difluoro-3-(triisopropylsilyl)prop-2-yn-1-yl)-3H-diazirin-3-yl)methanol, ≥95%

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone ≥95%

Sigma-Aldrich

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

Articoli

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Global Trade Item Number

SKUGTIN
900862-25MG4061833251287

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