900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinonimo/i: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₂H₁₄BrFO₂SSi
• Numero CAS: 2088828-99-1
• Peso molecolare: 349.29
• Codice UNSPSC: 12352200
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: powder or crystals
• Disponibilità: available only in USA
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=S(C(C(C#C[Si](C)(C)C)=C1)=CC=C1CBr)(F)=O

Descrizione

Applicazioni

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

• 1.Technology Spotlight: Trifunctional Probe Building Blocks
• 2.Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Pittogrammi: GHS02
• Avvertenze: Danger
• Indicazioni di pericolo: H242
• Consigli di prudenza: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classi di pericolo: Self-react. C
• Codice della classe di stoccaggio: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable