900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinonimo/i: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₁H₁₂BrFO₂SSi
• Numero CAS: 2088829-15-4
• Peso molecolare: 335.26
• Numero MDL: MFCD31579818
• Codice UNSPSC: 12352200
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: powder or crystals
• Impiego in reazioni chimiche: reaction type: click chemistry
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Si](C)(C)(C)C#Cc1cc(cc(c1)Br)[S](=O)(=O)F
• InChI: 1S/C11H12BrFO2SSi/c1-17(2,3)5-4-9-6-10(12)8-11(7-9)16(13,14)15/h6-8H,1-3H3; CUUVPHAGWQDSCZ-UHFFFAOYSA-N

Descrizione

Applicazioni

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable