900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Sinonimo/i: Carboxyl sulfonyl fluoride TMS-alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₂H₁₃FO₄SSi
• Numero CAS: 2088828-92-4
• Peso molecolare: 300.38
• Codice UNSPSC: 12352106
• NACRES: NA.22

Proprietà

• Saggio: ≥95%
• Forma fisica: powder or crystals
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC(C1=CC(C#C[Si](C)(C)C)=C(S(F)(=O)=O)C=C1)=O

Descrizione

Applicazioni

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifunctional Probe Building Blocks
Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable