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G5035

Sigma-Aldrich

Granulocyte-Macrophage Colony-Stimulating Factor human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sinônimo(s):

GM-CSF human

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About This Item

Número MDL:
MFCD00166611
Código UNSPSC:
12352202
NACRES:
NA.77

product name

Granulocyte-Macrophage Colony-Stimulating Factor human, GM-CSF, recombinant, expressed in E. coli, suitable for cell culture

fonte biológica

human

Nível de qualidade

200

recombinante

expressed in E. coli

Ensaio

≥98% (SDS-PAGE)

forma

lyophilized powder

potência

≤0.1 ng/mL EC50

peso molecular

14.6 kDa

embalagem

pkg of 4X5 μg
pkg of 5 μg

condição de armazenamento

avoid repeated freeze/thaw cycles

técnica(s)

cell culture | mammalian: suitable

Impurezas

≤1.000 EU/μg

cor

white

solubilidade

water: soluble 0.010 mL, clear, colorless

nº de adesão UniProt

P04141

temperatura de armazenamento

−20°C

Informações sobre genes

human ... CSF2(1437) , CSF2(1437)

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Descrição geral

Package size based on protein content

Ações bioquímicas/fisiológicas

Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth and differentiation factor for cells in the granulocyte, macrophage and eosinophil lineage. GM-CSF stimulates colony formation from pluripotential progenitor cells at extremely low concentrations and is an essential survival and proliferative factor for hematopoietic progenitor cells in all divisions up to maturity. It also stimulates growth in some epithelial cells and osteoclasts. GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a single chain glycoprotein containing 128 amino acids for human with a conserved disulfide bond. Human and murine GM-CSF share approx. 54% sequence homology and do not cross-react in bioactivity.

forma física

Lyophilized from a 0.2 μm filtered, 10 mM sodium citrate, pH 3.5 solution.

Nota de análise

The proliferative activity of human GM-CSF is tested in culture using human TF-1 cells.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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