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M6518

Sigma-Aldrich

Macrophage Colony-Stimulating Factor human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sinônimo(s):

MCSF

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About This Item

Número MDL:
MFCD00166591
Código UNSPSC:
12352202
NACRES:
NA.77

product name

Macrophage Colony-Stimulating Factor human, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

fonte biológica

human

Nível de qualidade

200

recombinante

expressed in E. coli

Ensaio

≥98% (SDS-PAGE and HPLC)

forma

lyophilized powder

potência

0.500-5.000 ng/mL ED50

qualidade

endotoxin tested

peso molecular

dimer 37 kDa

embalagem

pkg of 10 μg

técnica(s)

cell culture | mammalian: suitable

Impurezas

≤1.000 EU/μg

cor

white

nº de adesão UniProt

P09603

temperatura de armazenamento

−20°C

Informações sobre genes

human ... CSF1(1435)

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Descrição geral

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

Aplicação

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

Ações bioquímicas/fisiológicas

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

Outras notas

159 amino acids including N-terminal methionine (each monomer).

forma física

Lyophilized from a sterile filtered buffered solution.

Nota de análise

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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