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T1600000

Acetato de DL-α-tocoferol

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Acetato de all-rac-α-tocoferil, Acetato de vitamina E

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About This Item

Fórmula empírica (Notação de Hill):
C31H52O3
Número CAS:
7695-91-2
Peso molecular:
472.74
Beilstein:
97512
Número CE:
231-710-0
Número MDL:
MFCD00072042
Código UNSPSC:
41116107
ID de substância PubChem:
329826681
NACRES:
NA.24

fonte biológica

synthetic

grau

pharmaceutical primary standard

Agency

EP

família API

tocopherol

Formulário

liquid

fabricante/nome comercial

EDQM

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

densidade

0.96 g/mL at 20 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

chave InChI

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. α-Tocopherol acetate, a supplement of α-tocopherol, is an active form of vitamin E. This lipid-soluble antioxidant is found in whole grains, nuts, and oils. It is known to scavenge reactive oxygen species by interacting with lipids during oxidative stress.

Aplicação

α-Tocopherol acetate may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

No data available

Ponto de fulgor (°C)

No data available

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Certificados de análise (COA)

Lot/Batch Number

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(+)-α-Tocopherol acetate BioReagent, suitable for insect cell culture, ~1360 IU/g

Sigma-Aldrich

T1157

(+)-α-Tocopherol acetate

Vitamin E acetate-(trimethyl-d9) 98 atom % D, 98% (CP)

Sigma-Aldrich

615366

Vitamin E acetate-(trimethyl-d9)

all-rac-α-Tocopheryl acetate (Vitamin E acetate), EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC

SAFC

5.00952

all-rac-α-Tocopheryl acetate

Dexpanthenol European Pharmacopoeia (EP) Reference Standard

D0730000

Dexpanthenol

(±)-α-Tocoferol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1031

(±)-α-Tocoferol

(±)-α-Tocoferol dry powder, (50 g all-rac-a-tocopheryl acetate in 100 g subst), EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

SAFC

5.00859

(±)-α-Tocoferol

(±)-α-Tocoferol analytical standard

Supelco

47783

(±)-α-Tocoferol

all-rac-α-Tocopherol EMPROVE® ESSENTIAL Ph Eur,BP,USP,E 307

SAFC

5.00949

all-rac-α-Tocopherol

ANTIOXIDANTS-Role of Antioxidant Nutrients in Defense Systems
Encyclopedia of food sciences and nutrition, 282-289 (2003)
RRR-?-Tocopheryl acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3804-3805 (2013)
Determination of eight water-and fat-soluble vitamins in multi-vitamin pharmaceutical formulations by high-performance liquid chromatography
Moreno P and Salvado V
Journal of Chromatography A, 870(1-2), 207-215 (2000)
Flow injection spectrophotometric determination of vitamin E in pharmaceuticals, milk powder and blood serum using potassium ferricyanide-Fe (III) detection system
Jadoon S, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 21(6), 712-715 (2010)
The role of alpha-tocopherol in plant stress tolerance
Munne-Bosch S
Journal of Plant Physiology, 162(7), 743-748 (2005)
Exibir todos os documentos relacionados

Protocolos

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

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