22880

Chloroacetyl chloride

purum, ≥99.0% (GC)

• Sinônimo(s): Chloroacetic chloride
• Fórmula linear: ClCH₂COCl
• Número CAS: 79-04-9
• Peso molecular: 112.94
• Beilstein: 605439
• Número CE: 201-171-6
• Número MDL: MFCD00000725
• Código UNSPSC: 12352100
• ID de substância PubChem: 329752357
• NACRES: NA.22

Propriedades

• densidade de vapor: 3.9 (vs air)
• Nível de qualidade: 200
• pressão de vapor: 60 mmHg ( 41.5 °C)
• grau: purum
• Ensaio: ≥99.0% (GC)
• Formulário: liquid
• índice de refração: n20/D 1.453 (lit.); n20/D 1.453
• p.e.: 105-106 °C (lit.)
• pf: −22 °C (lit.)
• solubilidade: water: insoluble
• densidade: 1.419 g/mL at 20 °C; 1.418 g/mL at 25 °C (lit.)
• grupo funcional: acyl chloride; chloro
• cadeia de caracteres SMILES: ClCC(Cl)=O
• InChI: 1S/C2H2Cl2O/c3-1-2(4)5/h1H2
• chave InChI: VGCXGMAHQTYDJK-UHFFFAOYSA-N

Descrição

Descrição geral

Chloroacetyl chloride is an aliphatic acid chloride.

Aplicação

Chloroacetyl chloride may be used to prepare:

• 2-chloro-N-(pyridine-2-yl)acetamide via N-acylation of pyridin-2-amine
• chloroacetyl cellulose by reacting with cellulose in N,N-dimethylformamide
• azetobenzothiazine derivatives by reacting with 1,3-benzothiazines in the presence of a base in refluxing toluene
• 2-chloro-1-(3,5-diaryl-4,5-dihydropyrazol-1-yl)-ethanones by reacting with 3,5-diaryl-4,5-dihydropyrazoles
• chloroacetyl isatins by reacting with isatins under microwave conditions

It acts as a linker during the grafting of pyrimethanil with chitosan.

Chloroacetyl chloride was used in the synthesis of N-hydrazino acetyl-sulphonamides.

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS05,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H301 + H311 + H331,H314,H372,H400
• Declarações de precaução: P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P314
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT RE 1
• Órgãos-alvo: Lungs
• Perigos de suplementos: EUH014,EUH029
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 212.0 °F - closed cup
• Ponto de fulgor (°C): 100 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter