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Merck
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Documentos Principais

W381829

Sigma-Aldrich

L-Alanine

≥99%

Sinônimo(s):

(S)-2-Aminopropionic acid, L-α-Aminopropionic acid

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About This Item

Fórmula empírica (Notação de Hill):
C3H7NO2
Número CAS:
Peso molecular:
89.09
Número FEMA:
3818
Beilstein:
1720248
Número CE:
Número MDL:
Código UNSPSC:
12164502
eCl@ss:
32160406
ID de substância PubChem:
Número de Flavis:
17.002
NACRES:
NA.21
Organoléptico:
sweet
fonte biológica:
synthetic
alérgeno alimentar:
no known allergens

fonte biológica

synthetic

Nível de qualidade

Ensaio

≥99%

Formulário

chunks
crystalline powder
powder

atividade óptica

[α]20/D +13.5 to +15.5°, c = 10 in 6 M HCl

solubilidade

H2O: soluble 89.1 g/L at 20 °C (completely)

aplicação(ões)

flavors and fragrances

Documentação

see Safety & Documentation for available documents

alérgeno alimentar

no known allergens

Organoléptico

sweet

cadeia de caracteres SMILES

C[C@H](N)C(O)=O

InChI

1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1

chave InChI

QNAYBMKLOCPYGJ-REOHCLBHSA-N

Informações sobre genes

human ... CA1(759) , CA2(760)

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Aplicação


  • Exposure to synthesized tribromobisphenol A and critical effects: Metabolic pathways, disease signature, and benchmark dose derivation.: This study provides insight into the metabolic pathways and disease signatures associated with exposure to synthesized tribromobisphenol A, emphasizing the critical role of L-alanine in mediating these effects (Kuang et al., 2024).

  • Prenylated indole diketopiperazine alkaloids as phosphatase inhibitors from the marine-derived fungus Talaromyces purpureogenus.: Identifies new prenylated indole diketopiperazine alkaloids from Talaromyces purpureogenus that act as potent phosphatase inhibitors, with L-alanine being key to their structure and bioactivity, offering potential for drug development (Liang et al., 2024).


Exoneração de responsabilidade

For R&D or non-EU Food use. Not for retail sale.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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L-Alanine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1110

L-Alanine

Mom Das et al.
Nucleic acids research, 42(6), 3943-3953 (2013-12-29)
Errors in protein synthesis due to mispairing of amino acids with tRNAs jeopardize cell viability. Several checkpoints to prevent formation of Ala- and Cys-tRNA(Pro) have been described, including the Ala-specific editing domain (INS) of most bacterial prolyl-tRNA synthetases (ProRSs) and
Florian Madura et al.
The Journal of biological chemistry, 288(26), 18766-18775 (2013-05-24)
The T-cell receptor (TCR) recognizes peptides bound to major histocompatibility molecules (MHC) and allows T-cells to interrogate the cellular proteome for internal anomalies from the cell surface. The TCR contacts both MHC and peptide in an interaction characterized by weak
J M Rhoads et al.
Journal of pediatric gastroenterology and nutrition, 9(2), 225-231 (1989-08-01)
We studied sodium-dependent uptake of L-alanine into small intestinal brush border membrane vesicles (BBMV) isolated from piglets 40 h after infection with transmissible gastroenteritis (TGE) virus. Vesicles from TGE-infected pigs and uninfected litter-mate controls showed comparable degrees of enrichment and
Lillian L Siu et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(19), 2477-2484 (2013-05-22)
The antiepidermal growth factor receptor monoclonal antibody cetuximab has improved survival in patients with metastatic, chemotherapy-refractory, wild-type K-RAS colorectal cancer. The addition of brivanib, a tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor and fibroblast growth factor receptor, to
Rachelle S Doody et al.
The New England journal of medicine, 369(4), 341-350 (2013-07-26)
Alzheimer's disease is characterized by the presence of cortical amyloid-beta (Aβ) protein plaques, which result from the sequential action of β-secretase and γ-secretase on amyloid precursor protein. Semagacestat is a small-molecule γ-secretase inhibitor that was developed as a potential treatment

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