900814

SLAP TM

≥95%

• Sinônimo(s): 2-(((Trimethylsilyl)methyl)thio)ethanamine
• Fórmula empírica (Notação de Hill): C₆H₁₇NSSi
• Número CAS: 1226877-72-0
• Peso molecular: 163.36
• Código UNSPSC: 12352200
• NACRES: NA.22

Propriedades

• Ensaio: ≥95%
• forma: liquid
• índice de refração: n/D 1.4811
• densidade: 0.90746 g/mL
• grupo funcional: amine; thioether
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: NCCSC[Si](C)(C)C

Descrição

Aplicação

When used with aliphatic or aromatic aldehydes, this silicon amine protocol (SLAP) reagent enables the photomediated synthesis of thiomorpholines and thiazepanes. For photocatalytic cross-coupling with this SLAP Reagent, Ir[(ppy)₂dtbbpy]PF₆ ((747769) is used with a recommended starting combination of Lewis acids Bi(OTf)₃ (633305) and Cu(OTf)₂ (283673) prior to subsequent substrate-specific optimization. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents and is well-suited for scale-up reactions.

Outras notas

• Technology Spotlight: SLAP Reagents for Piperazine Synthesis
• Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones
• Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents.
• Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 174.0 °F
• Ponto de fulgor (°C): 78.89 °C