G9003
D-Glutamine
≥98% (HPLC)
Sinônimo(s):
D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide
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About This Item
Fórmula empírica (Notação de Hill):
C5H10N2O3
Número CAS:
Peso molecular:
146.14
Beilstein:
1723796
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.32
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product name
D-Glutamine, ≥98% (HPLC)
Nível de qualidade
Ensaio
≥98% (HPLC)
forma
powder
cor
white
aplicação(ões)
cell analysis
cadeia de caracteres SMILES
N[C@H](CCC(N)=O)C(O)=O
InChI
1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1
chave InChI
ZDXPYRJPNDTMRX-GSVOUGTGSA-N
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Descrição geral
Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.
Aplicação
D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.
Ações bioquímicas/fisiológicas
Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.
Outras notas
Unnatural isomer of glutamine
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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American journal of physiology. Gastrointestinal and liver physiology, 287(3), G510-G517 (2004-08-28)
Role of L-glutamine in the protection of intestinal epithelium from acetaldehyde-induced disruption of barrier function was evaluated in Caco-2 cell monolayer. L-Glutamine reduced the acetaldehyde-induced decrease in transepithelilal electrical resistance and increase in permeability to inulin and lipopolysaccharide in a
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Chromatograms
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