G1251

L-Glutamic acid

≥99% (HPLC), suitable for microbiological culture, ReagentPlus^®

• Sinônimo(s): (S)-2-Aminopentanedioic acid, Glu
• Fórmula linear: HO₂CCH₂CH₂CH(NH₂)CO₂H
• Número CAS: 56-86-0
• Peso molecular: 147.13
• Beilstein: 1723801
• Número CE: 200-293-7
• Número MDL: MFCD00002634
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de substância PubChem: 24895052
• NACRES: NA.26

Propriedades

• product name: L-Glutamic acid, ReagentPlus^®, ≥99% (HPLC)
• Agency: suitable for SM 5210
• linha de produto: ReagentPlus^®
• Ensaio: ≥99% (HPLC)
• forma: powder
• técnica(s): microbiological culture: suitable
• cor: white to off-white
• pf: 205 °C (dec.) (lit.)
• solubilidade: 1 M HCl: soluble 100 mg/mL
• densidade: 1.54 g/cm³ at 20 °C
• traços de cátion: C: 40.4-41.2%; N: 9.2-9.8%
• cadeia de caracteres SMILES: N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
• chave InChI: WHUUTDBJXJRKMK-VKHMYHEASA-N
• Informações sobre genes: human ... CCR2(1231) , GRIA1(2890) , GRIA2(2891) , GRIA4(2893) , GRIK2(2898) , GRIK3(2899) , GRIK5(2901) , GRIN2B(2904) , GRM2(2912) , SLC1A1(6505) , SLC1A2(6506) ; rat ... Gria1(50592) , Grik1(29559) , Grik2(54257) , Grik4(24406) , Grin2a(24409) , Grm1(24414) , Grm2(24415) , Grm3(24416) , Grm4(24417) , Grm5(24418) , Grm6(24419) , Grm7(81672) , Slc1a2(29482)

Descrição

Aplicação

L-Glutamic acid has been used to enhance endogenous acetylcholine overflow. It has been used as a supplement in the growth medium of meat-Spoiling Pseudomonas fragi 72.

Ações bioquímicas/fisiológicas

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Glutamic acid, or glutamate, the salt form of glutamic acid, functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as γ-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways, that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle, and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase.
Glutamine serves as a source of energy for rapidly dividing cells comprising lymphocytes, enterocytes, macrophages and tumors. Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signaling. It is also known to be associated with the inhibition of apoptosis.

Informações legais

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)