900756

SLAP M

≥95%

• Sinônimo(s): 2-((Trimethylsilyl)methoxy)ethan-1-amine
• Fórmula empírica (Notação de Hill): C₆H₁₇NOSi
• Número CAS: 2093935-94-3
• Peso molecular: 147.29
• Código UNSPSC: 12352200

Propriedades

• Ensaio: ≥95%
• Formulário: liquid
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: NCCOC[Si](C)(C)C

Descrição

Aplicação

When used with aliphatic or aromatic aldehydes, this silicon amine protocol (SLAP) reagent enables the photomediated synthesis of thiomorpholines and thiazepanes. For photocatalytic cross-coupling with this SLAP Reagent, Ir[(ppy)₂dtbbpy]PF6 (747769) is used with a recommended starting combination of Lewis acids Bi(OTf)₃ (633305) and Cu(OTf)₂ (283673) prior to subsequent substrate-specific optimization. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents and is well-suited for scale-up reactions.

Outras notas

• Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents
• Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable