199303
Resazurina
certified by the Biological Stain Commission
Sinônimo(s):
7-Hidróxi-3H-fenoxazin-3-ona-10-óxido
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About This Item
Fórmula empírica (Notação de Hill):
C12H6NNaO4
Número CAS:
Peso molecular:
251.17
Beilstein:
3794971
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.47
Produtos recomendados
grau
certified by the Biological Stain Commission
Nível de qualidade
forma
powder
composição
Dye content, 75%
solubilidade
1 M NH4OH: 1 mg/mL
λmax
380 nm (2nd)
598 nm
aplicação(ões)
diagnostic assay manufacturing
hematology
histology
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
[Na+].[O-]c1ccc2c(OC3=CC(=O)C=CC3=[N+]2[O-])c1
InChI
1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1
chave InChI
IVGPGQSSDLDOLH-UHFFFAOYSA-M
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Descrição geral
Resazurin is a small N-oxide derivative of dihydroxyphenoxazone. It is a non-ionic dye containing a small and planar chromophore. It is a redox indicator and changes from bluish violet through pink to colorless upon reduction. It is also used as a pH indicator for Ph 3.5 to 6.5 wherein it changed from orange to bluish violet. It is commercially available as resazurin sodium salt, which is also known as 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt. It forms the red, fluorescent hydroxyphenoxazone resorufin on reduction and colorless hydroresorufin on further reduction.
Aplicação
Resazurin is mostly used as a biological redox indicator. The bioreduction of the dye reduces the amount of the oxidized form (blue) and concomitantly increases the fluorescent intermediate (red). Its applications include:
- the measurement of metabolic activity and the proliferation of living cells
- the detection of bacterial reduction in milk
- in viability assays as a component of culture media for the detection of viable bacteria
- to determine the number of motile sperm in sheep semen
- to assay lactate dehydrogenase
- as an analytical reagent to quantify L-glutamate
Para medição da atividade metabólica e proliferação de células vivas. A biorredução do corante reduz a quantidade da forma oxidada (azul) e aumenta, concomitantemente, o intermediário fluorescente (vermelho).
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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