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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Sinônimos:
EPND, GluN2A, NMDAR2A, NR2A
Espécies:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), chicken GRIN2A (427678), dog GRIN2A (490012), domestic cat GRIN2A (101086110), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265)
ID UniProtKB:
Q12879, O00669, Q17RZ6
ID do gene:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
239488
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Espécies
rat
D-013
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
PHR1018
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Espécies
human
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Espécies
human
R1276
Reversin 121, ≥97% (HPLC), powder,
Espécies
mouse, rat, human

Small Molecule - Allosteric Modulator

Número do produto
Descrição
Espécies
561479
4-Aminopiperidine, ,
Espécies
rat
K0250
Kainic acid monohydrate, ≥99% (TLC),
Espécies
human, mouse, rat
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Espécies
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
A78403
4-Aminopyridine, 98%,
Espécies
rat, human, mouse

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
G7126
Glicina, ReagentPlus®, ≥99% (HPLC),
Espécies
rat
G8898
Glicina, suitable for electrophoresis, ≥99%,
Espécies
rat
50046
Glicina, BioUltra, for molecular biology, ≥99.0% (NT),
Espécies
rat
G8790
Glicina, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Espécies
rat
G5417
Glicina, ,
Espécies
rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
04-901
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Reatividade de espécies
mouse, rat
Aplicação
western blot
07-632
Anticorpo antiNR2A, Upstate®, from rabbit,
Reatividade de espécies
mouse, rat
Aplicação
immunoprecipitation (IP)
western blot
AB1555P
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Reatividade de espécies
fish, human, mouse, rat
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
ABN2251
Anti-phospho NMDAR2A (Ser1459), ,
Reatividade de espécies
human
Aplicação
immunocytochemistry
western blot
SAB5200888
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reatividade de espécies
human, mouse, rat
Aplicação
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Espécies
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Espécies
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Espécies
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
I5109
Indole-2-carboxylic acid, 98%,
Espécies
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Espécies
rat, mouse, human
Q2128
Quisqualic acid, powder,
Espécies
rat
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Espécies
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Espécies
human

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
D23602
1,3-Diaminopropane, ≥99%,
Espécies
rat
308110
N,N′-Dimethyl-1,3-propanediamine, 97%,
Espécies
rat
549983
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Espécies
rat
D18609
1,3-Diamino-2-propanol, 95%,
Espécies
rat
127027
N-Methyl-1,3-diaminopropane, 98%,
Espécies
rat

esiRNA

Número do produto
Descrição
Espécies
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Espécies
human
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Espécies
mouse