857127P

17:0 Lyso PA

1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Synonim(y): heptadecanoyl lysophosphatidic acid; 1-heptadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(17:0/0:0); 17:0 LPA; 110679
• Wzór empiryczny (zapis Hilla): C₂₀H₄₀O₇PNa
• Numer CAS: 799268-66-9
• Masa cząsteczkowa: 446.49
• Kod UNSPSC: 51191904
• NACRES: NA.25

Właściwości

• Próba: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Postać: powder
• opakowanie: pkg of 1 × 25 mg (857127P-25mg)
• producent / nazwa handlowa: Avanti Polar Lipids 857127P
• typ lipidu: phospholipids; cardiolipins
• Warunki transportu: dry ice
• temp. przechowywania: −20°C

Opis

Opis ogólny

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100 nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.

Zastosowanie

17:0 Lyso PA is suitable to use as an internal standard:

• for mass spectrometric determination of lysophosphatidic acid molecular species in mouse peritoneal macrophages
• in the quantification of the lipid species released from extended synaptotagmin 2 (E-SYT2) expressed in mammalian cells by liquid chromatography with tandem mass spectrometry (LC-MS/MS)
• for the extraction of lipids from brain homogenate
• to extract lipids from the stomach washing solution for the determination of lysophosphatidic acid in a mouse stomach fluid

Działania biochem./fizjol.

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

Opakowanie

5 mL Amber Glass Screw Cap Vial (857127P-25mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): No data available
• Temperatura zapłonu (°C): No data available