SRP6516

アルブミン ヒト血漿由来

≥95% (SDS-PAGE)

• 別名: Albumin protein, human Albumin, human Albumin protein, human plasma, human plasma Albumin proteinHSA, native Albumin, native Albumin protein
• EC Number: 232-692-7
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: human
• アッセイ: ≥95% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: 66 kDa
• 包装: pkg of 1G
• 色: beige
• UniProtアクセッション番号: P02768
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ALB(213)

詳細

詳細

Human albumin is encoded by ALB gene that is mapped to human chromosome 4q. The gene is developmentally regulated and is synthesized by the liver. The encoded protein has a molar mass of 65,000 Da and consists of a single polypeptide chain of 585 amino acids.

アプリケーション

Albumin has been used in ion exchange chromatography to compare the albumin isolated from whole human plasma. It has been used to bind to phage clones in phage binding assay.

生物化学的／生理学的作用

Human albumin is a globular unglycosylated serum protein that makes up for more than half of the total plasma or serum proteins. It functions in the maintenance of COP (cellular oncotic pressure). It binds to hydrophobic organic anions such as, bilirubin, long-chain fatty acids and haematin and some cations such as magnesium and calcium. It also serves as a secondary or tertiary carrier for steroids, vitamin D and thyroxine. It is involved in the catabolism of prostaglandins and metabolism of certain endogenous substances, such as lipids, and eicosanoids. It acts as a plasma buffer and scavenges oxygen free radicals, thus reducing the pathological effects of certain inflammatory diseases. Mutation in the gene coding for albumin leads to familial dysalbuminaemic hyperthyroidism.

物理的形状

Lyophilized as a salt free solid.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H334
• 注意書き: P261 - P284 - P304 + P340 + P312 - P501
• 危険有害性の分類: Resp. Sens. 1A
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable