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由来生物
human
品質水準
アッセイ
≥96% (agarose gel electrophoresis)
フォーム
lyophilized powder
分子量
monomer calculated mol wt 66478 Da
テクニック
activity assay: suitable
不純物
HIV I and HIVII, HCV and HBsAg, tested negative
≤1.0 EU/mg endotoxin
溶解性
H2O: soluble 50 mg/mL
UniProtアクセッション番号
保管温度
2-8°C
SMILES記法
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI Key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
遺伝子情報
human ... ALB(213)
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詳細
Albumin is the most copious protein in blood plasma. Liver produces human albumin.
アプリケーション
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.
生物化学的／生理学的作用
アルブミンは体液中および動物と一部の植物の種子の組織中にみられる可溶性の単量体タンパク質です。血清アルブミンはステロイド、脂肪酸、甲状腺ホルモンの担体タンパク質として機能します。血清アルブミンは血液のコロイド浸透圧の調節にも不可欠です。
血清アルブミンはステロイド、脂肪酸、甲状腺ホルモンの担体タンパク質として機能し、血液のコロイド浸透圧の調節にも不可欠です。またアルブミンは、薬物(イブプロフェン、ワルファリンなど)を始めとした外因性物質に結合し、薬物動態に強く影響を及ぼします。アルブミンの酸化還元状態の変化につながる酸化ストレスは、その生理機能に様々な影響を及ぼします。
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.
その他情報
より詳細な情報につきましては、human serum albuminをご覧ください。
免責事項
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A5843-VAR:
A5843-5G:
A5843-BULK:
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Sam Coffey et al.
PloS one, 10(10), e0140417-e0140417 (2015-10-16)
Diabetes mellitus (DM) has become an epidemic, causing a significant decline in quality of life of individuals due to its multisystem involvement. Kidney is an important target organ in DM accounting for the majority of patients requiring renal replacement therapy
Edina Korça et al.
Scientific reports, 10(1), 17105-17105 (2020-10-15)
Advanced glycation endproducts (AGEs) are formed in a series of non-enzymatic reactions between reducing sugars and the amino groups of proteins and accumulate during aging, diabetes mellitus, chronic kidney disease and other chronic diseases. Accumulation of AGE-modifications alters protein structure
Yasutaka Kuroda et al.
The Journal of toxicological sciences, 45(6), 327-337 (2020-06-05)
Hydrolyzed wheat proteins (HWPs) contained in cosmetics have occasionally caused immediate-type hypersensitivity following repeated skin exposure. Although the Cosmetic Ingredient Review Expert Panel concluded that < 3,500 Da HWP is safe for use in cosmetics, it remains biologically unknown how
Miranda J Ridder et al.
Infection and immunity, 88(8) (2020-06-10)
Staphylococcus aureus fatty acid kinase FakA is necessary for the incorporation of exogenous fatty acids into the lipid membrane. We previously demonstrated that the inactivation of fakA leads to decreased α-hemolysin (Hla) production but increased expression of the proteases SspAB
Nitin Agrawal et al.
Lab on a chip, 8(12), 2054-2061 (2008-11-22)
Neutrophil directional migration in response to chemical gradients, also known as chemotaxis, is one of the key phenomena in the immune responses against bacterial infection. To better study neutrophils chemotaxis, several in vitro assays have been developed that replicate chemotactic
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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