A0862

A-740003

≥98% (HPLC)

• 別名: N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide
• 実験式（ヒル表記法）: C₂₆H₃₀N₆O₃
• CAS番号: 861393-28-4
• 分子量: 474.55
• MDL番号: MFCD09970333
• UNSPSCコード: 12352200
• PubChem Substance ID: 329770637
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to light brown
• 溶解性: DMSO: 10 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
• InChI: 1S/C26H30N6O3/c1-26(2,3)24(31-23(33)15-17-11-12-21(34-4)22(14-17)35-5)32-25(29-16-27)30-20-10-6-9-19-18(20)8-7-13-28-19/h6-14,24H,15H2,1-5H3,(H,31,33)(H2,29,30,32)
• InChI Key: PUHSRMSFDASMAE-UHFFFAOYSA-N

詳細

詳細

A-740003 is a highly affine and selective P2X7 receptor antagonist and is best for the progression of a radiotracer for imaging of neuroinflammation by positron emission tomography.

生物化学的／生理学的作用

A-740003 is a selective P2X7 purinoceptor antagonist.

特徴および利点

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable