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Merck

ESR1

estrogen receptor 1

別名:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
  • Mouse(13982) estrogen receptor 1 (alpha)
  • Rat(24890) estrogen receptor 1
  • Goat(100860768) estrogen receptor 1
  • sheep(443228) estrogen receptor 1
  • domestic guinea pig(100713276) estrogen receptor 1
  • Zebrafish(259252) estrogen receptor 1
  • dog(403640) estrogen receptor 1
  • cow(407238) estrogen receptor 1
  • Horse(791249) estrogen receptor 1
  • domestic cat(552888) estrogen receptor 1
  • chicken(396099) estrogen receptor 1
  • Thale Cress(837856) ethylene-responsive transcription factor ESR1

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Small Molecule - Activator

製品番号
詳細
Species
4-フェニルアゾフェノール, 98%,
Species
human
β-ニコチンアミドアデニンジヌクレオチド ナトリウム塩 from Saccharomyces cerevisiae, ,
Species
human
β-ニコチンアミドアデニンジヌクレオチド 水和物, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Species
human
trans-スチルベン, 96%,
Species
human, rat
β-ニコチンアミドアデニンジヌクレオチド 水和物, ≥95% (HPLC),
Species
human

Small Molecule - Agonist

製品番号
詳細
Species
17β-エストラジオール 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
β-エストラジオール, United States Pharmacopeia (USP) Reference Standard,
Species
human
エストラジオール, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Ethinyl estradiol, United States Pharmacopeia (USP) Reference Standard,
Species
human
Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
タモキシフェン, analytical standard,
Species
human
タモキシフェン クエン酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
タモキシフェン, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
タモキシフェン クエン酸塩, British Pharmacopoeia (BP) Reference Standard,
Species
human
タモキシフェン クエン酸塩, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
フタル酸ジブチル, 99%,
Species
mouse
フタル酸ベンジルブチル, 98%,
Species
mouse
ゼアラレノン, fungal mycotoxin,
Species
mouse
4-tert-オクチルフェノール, 97%,
Species
mouse
アトラジン, analytical standard,
Species
mouse

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunohistochemistry

western blot
抗ESR1 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
western blot
抗エストロゲン関連受容体α抗体, Upstate®, from rabbit,
交差性
hamster, human, mouse, rat
アプリケーション
electrophoretic mobility shift assay
immunohistochemistry

immunoprecipitation (IP)

western blot
Rabbit anti-Estrogen Receptor Alpha Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
交差性
human
アプリケーション
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ビシクロヘキシル, 99%,
Species
human
ビフェニル, ReagentPlus®, 99.5%,
Species
human
ビフェニル, ≥99%,
Species
human
4,4′-ジヒドロキシビフェニル, 97%,
Species
human
4′-ヒドロキシ-4-ビフェニルカルボニトリル, 97%,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
4-ヒドロキシエストラジオール, ,
Species
rat, human
プロゲステロン, VETRANAL®, analytical standard,
Species
human
タモキシフェン, ≥99%,
Species
human, rat
テストステロン, ≥98%,
Species
mouse, human, rat
プロゲステロン, powder, BioReagent, suitable for cell culture,
Species
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
α-エストラジオール, powder, ≥98% (TLC),
Species
human, rat
メドロキシプロゲステロン17-アセタート, ≥97% (HPLC),
Species
human, rat
エストラジオール, meets USP testing specifications,
Species
human, mouse, rat
β-エストラジオール, BioReagent, powder, suitable for cell culture,
Species
human, mouse, rat
β-エストラジオール, ≥98%,
Species
human, mouse, rat

Proteins

製品番号
詳細
Species
エストロゲンレセプターα ヒト, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human ESR1,
Species
human