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Merck

SAB4500811

Sigma-Aldrich

Anti-Estrogen Receptor-α antibody produced in rabbit

affinity isolated antibody

別名:

ER, ESR

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

antigen 66 kDa

化学種の反応性

rat, mouse, human

濃度

~1 mg/mL

テクニック

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... ESR1(2099)

関連するカテゴリー

詳細

Anti-Estrogen Receptor-α Antibody detects endogenous levels of total Estrogen Receptor-α protein.

Estrogen receptor alpha (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.

免疫原

The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha.

Immunogen Range: 71-120

生物化学的/生理学的作用

Estrogen receptor alpha (ERα) is involved in immune and inflammatory response. Aberrations in ESR1 results in Mayer-Rokitansky-Küster-Hauser syndrome that is associated with the congenital absence of the uterus and the upper two-thirds of the vagina.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

ER?36, a variant of estrogen receptor ?, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
Yan Y, et al.
PLoS ONE, 12(10) (2017)
ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1
Dunbier AK, et al.
PLoS Genetics, 7(4) (2011)
Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ER? in SUM-44 breast cancer cells and is associated with ER? over-expression in breast cancer
Irish JC, et al.
Molecular Oncology, 10(6), 850-865 (2016)
Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Kuster-Hauser syndrome
Brucker SY, et al.
Acta Obstetricia et Gynecologica Scandinavica, 96(11), 1338-1346 (2017)
Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease
Linares PM, et al.
Digestive Diseases and Sciences, 62(10), 2744-2754 (2017)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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