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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 66 kDa
化学種の反応性
rat, mouse, human
濃度
~1 mg/mL
テクニック
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ESR1(2099)
関連するカテゴリー
詳細
Anti-Estrogen Receptor-α Antibody detects endogenous levels of total Estrogen Receptor-α protein.
Estrogen receptor alpha (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.
免疫原
The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha.
Immunogen Range: 71-120
Immunogen Range: 71-120
生物化学的/生理学的作用
Estrogen receptor alpha (ERα) is involved in immune and inflammatory response. Aberrations in ESR1 results in Mayer-Rokitansky-Küster-Hauser syndrome that is associated with the congenital absence of the uterus and the upper two-thirds of the vagina.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
ER?36, a variant of estrogen receptor ?, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
PLoS ONE, 12(10) (2017)
ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1
PLoS Genetics, 7(4) (2011)
Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ER? in SUM-44 breast cancer cells and is associated with ER? over-expression in breast cancer
Molecular Oncology, 10(6), 850-865 (2016)
Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Kuster-Hauser syndrome
Acta Obstetricia et Gynecologica Scandinavica, 96(11), 1338-1346 (2017)
Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease
Digestive Diseases and Sciences, 62(10), 2744-2754 (2017)
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