A1520

α-Amylase Inhibitor

≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase), ≥1000 inhibitor U/mg protein (using human salivary α-amylase), lyophilized powder

• Número MDL: MFCD00130475
• Código UNSPSC: 12352202
• NACRES: NA.77

Propriedades

• product name: α-Amylase Inhibitor from Triticum aestivum (wheat seed), Type I, lyophilized powder
• fonte biológica: Triticum estivum
• Nível de qualidade: 200
• tipo: Type I
• forma: lyophilized powder
• atividade específica: ≥1000 inhibitor U/mg protein (using human salivary α-amylase); ≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase)
• composição: Protein, 35-65% biuret
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

α-Amylases are endoglycosidases, that are classified into glycosyl hydrolase family 13 (1-3).

Aplicação

α-Amylase Inhibitor from Triticum aestivum (wheat seed) has been used to determine its effects on salivary gland (SG) amylase activity. It has also been used to inhibit the activity from the extract from Bemisia tabaci.

Ações bioquímicas/fisiológicas

α-Amylases can hydrolyze α-(1,4)-D-glycosidic linkages. It participates in the breakdown of starch and glycogen. Inhibiting this enzyme can be used as a strategy to treat dental caries, diabetes, obesity and periodontal diseases.

Competitive inhibitor of human salivary α-amylase. K_I = 2.9 nM, compared to a K_M of 5.9 mM (calculated per mole of α-1,4-linked maltose residues).

Definição da unidade

One unit will reduce the activity of two units of α-amylase (A0521) by 50% after pre-incubation at 25 °C.

forma física

Lyophilized powder containing buffer salts as sodium phosphate.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)