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Key Documents

10080

Sigma-Aldrich

α-Amylase from hog pancreas

powder, ~50 U/mg

Sinônimo(s):

α-Amylase Enzyme

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About This Item

Número CE:
Código UNSPSC:
12352204
NACRES:
NA.54

fonte biológica

hog pancreas

Nível de qualidade

forma

powder

atividade específica

~50 U/mg

temperatura de armazenamento

−20°C

Descrição geral

Pancreatic α-amylase is produced by the pancreatic acinar cells and released into the duodenum. It is a major molecule of pancreatic fluid.

Aplicação

α-Amylase from hog pancreas has been used:
  • in the in vitro digestion system to study the hydrolysis of pea globulins
  • in vitro α-amylase inhibition study
  • to prepare digestive juice (salivary juice) for the in vitro model of the human digestion system

Ações bioquímicas/fisiológicas

α-Amylase is a starch hydrolase, for glucose production, important for energy acquisition. It catalyzes the hydrolysis of α-1,4-glycosidic linkages in starch to form glucose, maltose, and maltotriose units. In mammals, α-amylase regulates the sugar assimilation by reducing the glucose uptake by Na+/glucose cotransporter 1 (SGLT1) and stimulating glycoprotein N-glycans mediated starch digestion. α-Amylase inhibitors are associated with the treatment of type 2 diabetes mellitus. α-Amylases are widely known industrial enzymes used in food, detergent, textile, fermentation, and pharmaceutical industries.

Definição da unidade

1 U corresponds to the amount of enzyme which liberates 1 μmol maltose per minute at pH 6.9 and 25°C (starch acc. to Zulkowsky, Cat. No. 85642, as substrate)

Outras notas

Optimum pH and temperature 6.9 and 53 °C, respectively; calcium is required for activity and also prevents degradation by trypsin; Characterization.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Resp. Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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