PHR1258

Cloroquina

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): N⁴-(7-cloro-4-quinolinil)-N¹,N¹-dimetil-1,4-pentanodiamina
• Fórmula empírica (Notação de Hill): C₁₈H₂₆ClN₃ · 2H₃PO₄
• Número CAS: 50-63-5
• Peso molecular: 515.86
• Beilstein: 4223142
• Número CE: 200-055-2
• Número MDL: MFCD00069852
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823259
• NACRES: NA.24

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 300
• grau: certified reference material; pharmaceutical secondary standard
• Agency: BP; EP; USP; traceable to USP 1118000
• pressão de vapor: <0.0000001 kPa ( 25 °C)
• família API: chloroquine
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 1 g
• condição de armazenamento: protect from light
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• cor: white to yellow
• pH: 3.5-4.5 (10% in aqueous solution, pH <6.0)
• pf: 200 °C (dec.) (lit.)
• solubilidade: water: 50 g/L; benzene: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
• chave InChI: QKICWELGRMTQCR-UHFFFAOYSA-N

Descrição

Descrição geral

Chloroquine phosphate is a phosphate salt of chloroquine. It belongs to the class of aminoquinoline drugs utilized as antimalarials and amebicides.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Chloroquine phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin-layer chromatography (TLC) and liquid chromatography (LC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB3715 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable