5.43899

NMP

for liquid chromatography LiChrosolv^®

• Sinônimo(s): 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• Fórmula empírica (Notação de Hill): C₅H₉NO
• Número CAS: 872-50-4
• Peso molecular: 99.13
• Número MDL: MFCD00003193
• Código UNSPSC: 41116105
• Número do índice EC: 212-828-1
• NACRES: NA.03

Propriedades

• product name: 1-Methyl-2-pyrrolidone, for liquid chromatography LiChrosolv^®
• pressão de vapor: 0.32 hPa ( 20 °C)
• Nível de qualidade: 100
• linha de produto: LiChrosolv^®
• grau: isocratic
• Ensaio: ≥99.5% (GC)
• forma: liquid
• temperatura de autoignição: 245 °C
• Lim. expl.: 1.3-9.5 % (v/v)
• técnica(s): HPLC: suitable
• Impurezas: ≤0.05% Water
• transmitância: 300 nm, ≥50%; 325 nm, ≥90%; 350 nm, ≥97%; 400 nm, ≥99%
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• pb: 202 °C/1013 hPa
• pf: -24 °C
• temperatura de transição: flash point 91 °C
• solubilidade: 1000 g/L
• densidade: 1.03 g/cm³ at 20 °C
• temperatura de armazenamento: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• chave InChI: SECXISVLQFMRJM-UHFFFAOYSA-N

Descrição

Aplicação

• Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine: This study utilizes 1-Methyl-2-pyrrolidone (NMP) as a high-purity solvent in the formulation of a transdermal bioadhesive system, enhancing the solubility and delivery of antimalarial drugs. The application highlights NMP′s role in pharmaceutical formulations, particularly in improving drug efficacy and patient compliance (Volpe-Zanutto et al., 2021).

Nota de análise

Purity (GC): ≥ 99.5 %
Water: ≤ 0.05 %
Transmission (at 300 nm): ≥ 50 %
Transmission (at 325 nm): ≥ 90 %
Transmission (at 350 nm): ≥ 97 %
Transmission (at 400 nm): ≥ 99 %

Outras notas

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Informações legais

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS07,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H315 - H319 - H335 - H360D
• Declarações de precaução: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 195.8 °F - Pensky-Martens closed cup
• Ponto de fulgor (°C): 91 °C - Pensky-Martens closed cup