19-148
Bafilomycin A1
Sinônimo(s):
Bafilomycin A
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About This Item
Código UNSPSC:
12352106
eCl@ss:
32160405
NACRES:
NA.41
Produtos recomendados
descrição
Bafilomycin A1 is a specific potent inhibitor of vacuolar-type H+-ATPases, and blocks lysosomal cholesterol transport in macrophages.
Nível de qualidade
fabricante/nome comercial
Upstate®
técnica(s)
activity assay: suitable (kinase)
temperatura de armazenamento
−20°C
Aplicação
Bafilomycin A1 has been used:
- as an autophagy inhibitor to study its effect on traumatic brain injury (TBI)-induced cell death and lesions in mice
- to treat neurons for pH luorin assays to measure endocytosis during synaptic activity
- to block autophagy in mouse embryonic fibroblasts
Ações bioquímicas/fisiológicas
Inhibitor Type: Kinase
forma física
C35H58O9
Armazenamento e estabilidade
3 years at -20°C
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
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