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W355690

Sigma-Aldrich

Isopropyl myristate

≥98%

Sinônimo(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Fórmula linear:
CH3(CH2)12COOCH(CH3)2
Número CAS:
110-27-0
Peso molecular:
270.45
Número FEMA:
3556
Beilstein:
1781127
Número CE:
203-751-4
Conselho da Europa nº:
386
Número MDL:
MFCD00008982
Código UNSPSC:
12164502
ID de substância PubChem:
24901779
Número de Flavis:
9.105
NACRES:
NA.21

fonte biológica

synthetic

Nível de qualidade

400

grau

Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines

conformidade reg.

EU Regulation 1223/2009

Ensaio

≥98%

índice de refração

n20/D 1.434 (lit.)

pb

193 °C/20 mmHg (lit.)

pf

~3 °C (lit.)

densidade

0.85 g/mL at 25 °C (lit.)

aplicação(ões)

flavors and fragrances

Documentação

see Safety & Documentation for available documents

alérgeno alimentar

no known allergens

alérgeno de fragrância

no known allergens

Organoléptico

faint; fatty; oily

cadeia de caracteres SMILES

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

chave InChI

AXISYYRBXTVTFY-UHFFFAOYSA-N

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Descrição geral

Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.

Aplicação


  • Development of Nanostructured Lipid Carrier-Loaded Flavonoid-Enriched Zingiber officinale.: This research develops nanostructured lipid carriers for flavonoids derived from Zingiber officinale, employing Isopropyl myristate to stabilize these carriers and improve bioactive compound delivery (Shazwani SS et al., 2024).

  • Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin.: The study compares various enhancement methods for transdermal drug delivery, including the use of Isopropyl myristate, highlighting its effectiveness in permeation enhancement techniques (Karve T et al., 2024).

  • Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.: This research optimizes liposome formulations containing Zanthoxylum alkylamides, with Isopropyl myristate being crucial in liposome stability and absorption characteristics (Wang R et al., 2024).

Ações bioquímicas/fisiológicas

Odor at 1.0%
Taste at 10 ppm

Exoneração de responsabilidade

For R&D or non-EU Food use. Not for retail sale.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

awg

Ponto de fulgor (°F)

>302.0 °F

Ponto de fulgor (°C)

> 150 °C

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Handbook of Preservatives, 425-425 (2004)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
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