Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

M0757

Sigma-Aldrich

Isopropyl myristate

≥90% (GC)

Sinônimo(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Fórmula linear:
CH3(CH2)12COOCH(CH3)2
Número CAS:
Peso molecular:
270.45
Beilstein:
1781127
Número CE:
Número MDL:
Código UNSPSC:
12352211
ID de substância PubChem:
NACRES:
NA.25

fonte biológica

synthetic (organic)

Ensaio

≥90% (GC)

Formulário

liquid

índice de refração

n20/D 1.434 (lit.)

p.e.

193 °C/20 mmHg (lit.)

pf

~3 °C (lit.)

densidade

0.85 g/mL at 25 °C (lit.)

grupo funcional

ester

tipo de lipídio

saturated FAs

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

chave InChI

AXISYYRBXTVTFY-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação


  • Formulation design and development of matrix diffusion controlled transdermal drug delivery of glimepiride.: This study discusses the design of a transdermal drug delivery system for glimepiride, utilizing matrix diffusion mechanisms potentially incorporating Isopropyl Myristate to enhance permeation (Akram et al., 2018).

  • Investigation of microemulsion and microemulsion gel formulations for dermal delivery of clotrimazole.: This article evaluates formulations incorporating Isopropyl Myristate for enhanced dermal delivery of clotrimazole, highlighting its role in improving drug solubility and skin absorption rates (Zhang and Michniak-Kohn, 2018).

Ações bioquímicas/fisiológicas

Isopropyl myristate (myristic acid isopropyl ester) is used to change the physicochemical characteristics of microsheres such as poly(lactic-co-glycolic acid) (PLGA) microspheres. Isopropyl myristate is used as a oil phase component in the formulation of microemulsion systems.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

awg

Ponto de fulgor (°F)

>302.0 °F

Ponto de fulgor (°C)

> 150 °C

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Mahendra Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 895-916 (2020-10-19)
The eye is the specialized part of the body and is comprised of numerous physiological ocular barriers that limit the drug absorption at the action site. Regardless of various efforts, efficient topical ophthalmic drug delivery remains unsolved, and thus, it
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica