919381

CCW16

≥95%

• Sinônimo(s): N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide, E3 ubiquitin ligase ligand, Ligand for PROTAC^® research, RNF4-targeting ligand
• Fórmula empírica (Notação de Hill): C₂₂H₂₀ClNO₃
• Número CAS: 2361138-33-0
• Peso molecular: 381.85
• NACRES: NA.22

Propriedades

• ligand: CCW16
• Nível de qualidade: 100
• Ensaio: ≥95%
• forma: powder
• adequação da reação: reagent type: ligand
• grupo funcional: amine
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1

Descrição

Aplicação

CCW16 is targeting ligand for the E3 ubiquitin ligase RNF4 (RING finger protein 4) and can be used in targeted protein degradation (TPD) research or in the synthesis of protein degraders. Learn more about proteolysis-targeting chimeras (PROTAC degraders) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation.

Outras notas

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Targeted Protein Degradation by Small Molecules

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Informações legais

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informações de segurança

• Pictogramas: GHS09
• Palavra indicadora: Warning
• Frases de perigo: H410
• Declarações de precaução: P273 - P391 - P501
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable