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Key Documents

Inne dokumenty

T1782

Sigma-Aldrich

(+)-γ-Tocopherol

≥96% (HPLC)

Synonim(y):

gamma-Tocopherol, (R,R,R)-γ-Tocopherol, 7,8-Dimethyltocol

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About This Item

Wzór empiryczny (zapis Hilla):
C28H48O2
Numer CAS:
54-28-4
Masa cząsteczkowa:
416.68
Beilstein:
93072
Numer WE:
200-201-5
Numer MDL:
MFCD00066529
Kod UNSPSC:
12352211
eCl@ss:
34058016
Identyfikator substancji w PubChem:
24899992
NACRES:
NA.79

Próba

≥96% (HPLC)

Postać

liquid

metody

HPLC: suitable

kolor

dark brown
 colorless to dark yellow

temp. przechowywania

2-8°C

ciąg SMILES

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1

InChI

1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1

Klucz InChI

QUEDXNHFTDJVIY-DQCZWYHMSA-N

informacje o genach

human ... HMGCR(3156)

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Zastosowanie

(+)-γ-Tocopherol has been used:
  • as reference material for the quantification of γ-tocopherol in the oil sample using high performance liquid chromatography with diode array detector (HPLC/DAD)(192}
  • as a component of diet to feed vitamin-E-depleted rats to study its effects
  • as an additive in the feed to study its effects in reducing dietary induced oxidative stress in vivo and improving meat lipid stability in broilers

Działania biochem./fizjol.

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble antioxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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(+)-α-Tocopherol from vegetable oil, Type V, ~1000 IU/g

Sigma-Aldrich

T3634

(+)-α-Tocopherol

δ-Tocotrienol analytical standard

Supelco

69745

δ-Tocotrienol

γ-Tocotrienol analytical standard

Supelco

49634

γ-Tocotrienol

Alpha Tocopherol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1031

Alpha Tocopherol

DL-α-Tocopherol acetate ≥96% (HPLC)

Sigma-Aldrich

T3376

DL-α-Tocopherol acetate

vibrant-m

NIST3278

Tocopherols in edible oils

Graded dietary levels of RRR-gamma-tocopherol induce a marked increase in the concentrations of alpha-and gamma-tocopherol in nervous tissues, heart, liver and muscle of vitamin-E-deficient rats
Clement M, et al.
Biochimica et biophysica acta. General subjects, 1334(2-3), 173-118 (1997)
Characterization of oil extracted from the kernel of the fruit of cumare?s palm (Astrocaryum chambira Barret)
Ramirez-Nino MA, et al.
Revista da Faculdade de Odontologia de Aracatuba, 71(1), 8415-8422 (2018)
Chandra K Singh et al.
Oncotarget, 5(11), 3651-3661 (2014-07-09)
Studies have shown that vitamin E and selenium possess antiproliferative effects against prostate cancer (PCa). However, results from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) suggest that vitamin E (α-tocopheryl acetate; 400 mg) and/or selenium (L-selenomethionine; 200 μg)
The potency of alpha-and gamma-tocopherol, and their combination, in reducing dietary induced oxidative stress in vivo and improving meat lipid stability in broilers
Tomavzin U, et al.
Archiv fur Geflugelkunde, 77, 266-274 (2013)
P C Allen et al.
Poultry science, 81(1), 41-48 (2002-03-12)
In two trials, broiler chickens, processed similarly to those placed in commercial operation, were fed, from 1 d of age, a range (13 to 200 ppm) of DL-alpha-tocopheryl acetate (VE-AC) levels, and the effects on the pathology of Eimeria maxima
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Protokoły

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications

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