258024

α-Tocopherol

≥95.5%

• Synonim(y): (±)-α-Tocopherol, DL-all-rac-α-Tocopherol, Vitamin E
• Wzór empiryczny (zapis Hilla): C₂₉H₅₀O₂
• Numer CAS: 10191-41-0
• Masa cząsteczkowa: 430.71
• Beilstein: 94012
• Numer WE: 233-466-0
• Numer MDL: MFCD00006848
• Kod UNSPSC: 12352205
• eCl@ss: 34058016
• Identyfikator substancji w PubChem: 57648149

Właściwości

• pochodzenie biologiczne: synthetic
• Poziom jakości: 200
• Próba: ≥95.5%
• Postać: liquid
• metody: HPLC: suitable
• kolor: faint brown to brown; yellow to very dark yellow
• gęstość: 0.950 g/mL at 20 °C (lit.)
• Zastosowanie: cell analysis
• temp. przechowywania: 2-8°C
• ciąg SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
• InChI: 1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
• Klucz InChI: GVJHHUAWPYXKBD-UHFFFAOYSA-N

Opis

Opis ogólny

α-Tocopherol is the active form of vitamin E. It functions as an hydroperoxyl radical scavenger and protects the organism from oxidative damage. α-Tocopherol plays a crucial role in cell signalling and regulating immune responses. α-Tocopherol deficiency is associated with abetalipoproteinemia, cystic fibrosis and celiac disease. It has antiproliferative effects. It inhibits arsenite-induced damage of human fibroblasts.

Zastosowanie

α-Tocopherol has been used:

• as a standard to determine its concentration by reverse-phase high-performance liquid chromatography
• to study its rescue effects on chlorine dioxide (ClO₂) cytotoxicity
• to assess its protective effects on acetaminophen (APAP)-mediated liver damage

Działania biochem./fizjol.

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H317
• Zwroty wskazujące środki ostrożności: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Klasyfikacja zagrożeń: Skin Sens. 1
• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Środki ochrony indywidualnej: Eyeshields, Gloves