PHR1376

Loratadine

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Loratadine, 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine
• Wzór empiryczny (zapis Hilla): C₂₂H₂₃N₂O₂Cl
• Numer CAS: 79794-75-5
• Masa cząsteczkowa: 382.88
• Numer MDL: MFCD00672869
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329823353
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to BP 874; traceable to Ph. Eur. Y0000688; traceable to USP 1370270
• rodzina API: loratadine
• Certyfikat analizy: current certificate can be downloaded
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: 2-30°C
• ciąg SMILES: CCOC(=O)N1CC\C(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
• InChI: 1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
• Klucz InChI: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• informacje o genach: human ... HRH1(3269)

Opis

Opis ogólny

Loratadine belongs to the class of H1-antihistamine drugs, with non-sedating properties, and is widely used in the treatment of allergies.

Zastosowanie

Loratadine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Działania biochem./fizjol.

Non-sedating histamine H₁-receptor antagonist.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC3785 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable