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Merck

PHR1005

Supelco

Acetaminophen

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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About This Item

Wzór liniowy:
CH3CONHC6H4OH
Numer CAS:
Masa cząsteczkowa:
151.16
Beilstein:
2208089
Numer WE:
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

agency

traceable to BP 371
traceable to Ph. Eur. P030000
traceable to USP 1003009

rodzina API

paracetamol, acetaminophen

Certyfikat analizy

current certificate can be downloaded

metody

HPLC: suitable
gas chromatography (GC): suitable

mp

168-172 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-30°C

ciąg SMILES

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

Klucz InChI

RZVAJINKPMORJF-UHFFFAOYSA-N

informacje o genach

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Opis ogólny

Acetaminophen is a drug, which possesses pharmacological properties like antipyretic and analgesic property.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Acetaminophen may be used as a standard in the determination of acetaminophen in human serum or plasma samples using spectrophotometric technique. It may also be used as a standard in the estimation of acetaminophen in pharmaceutical formulations using high performance liquid chromatography (HPLC).
Analgesic.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAB7782 in the slot below. This is an example certificate only and may not be the lot that you receive.

Polecane produkty

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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Numer produktu
Opis
Cennik

Piktogramy

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Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Acute Tox. 4 Oral

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

364.3 °F - Pensky-Martens closed cup

Temperatura zapłonu (°C)

184.6 °C - Pensky-Martens closed cup


Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Simultaneous high-performance liquid chromatographic stability-indicating analysis of acetaminophen and codeine phosphate in tablets and capsules
Sisco.RW, et al.
Journal of Chromatography A, 348, 253-263 (1985)
Spectrophotometric Screening Method for Acetaminophen in Serum and Plasma
Liu.ZT and Oka.HK
Clinical Chemistry, 26, 69-71 (1980)
Reversed-phase HPLC method for the estimation of acetaminophen, ibuprofen and chlorzoxazone in formulations
Ravisankar.S, et al.
Talanta, 46, 1577-1581 (1998)
S M de Morais et al.
Gastroenterology, 102(2), 577-586 (1992-02-01)
Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
Edward Munsterhjelm et al.
Anesthesiology, 103(4), 712-717 (2005-09-30)
Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet

Produkty

Separation of Acetaminophen, meets USP testing specifications, 98.0-102.0%, powder; Caffeine, meets USP testing specifications, anhydrous; Benzoic acid, meets USP testing specifications; Aspirin, meets USP testing specifications

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