PHR1224

Aminocaproic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): 6-Aminocaproic acid, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
• Wzór liniowy: H₂N(CH₂)₅CO₂H
• Numer CAS: 60-32-2
• Masa cząsteczkowa: 131.17
• Beilstein: 906872
• Numer WE: 200-469-3
• Numer MDL: MFCD00008238
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329823230
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to Ph. Eur. A0420000; traceable to USP 1021000
• rodzina API: aminocaproic acid
• Certyfikat analizy: current certificate can be downloaded
• metody: HPLC: suitable; gas chromatography (GC): suitable
• mp: 207-209 °C (dec.) (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-30°C
• ciąg SMILES: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• Klucz InChI: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• informacje o genach: human ... PLAT(5327) , PLG(5340)

Opis

Opis ogólny

Aminocaproic acid is a synthetic inhibitor of fibrinolysis and is utilized for the control of excessive bleeding in patients with amegakaryocytic thrombocytopenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Aminocaproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry and in bulk and injectable forms using colorimetric method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Działania biochem./fizjol.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAA9036 in the slot below. This is an example certificate only and may not be the lot that you receive.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable