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Merck

PHR1068

Supelco

Ethylenediaminetetraacetic acid disodium salt dihydrate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

Edetate Disodium, Edetate disodium dihydrate, Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2

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About This Item

Wzór empiryczny (zapis Hilla):
C10H14N2Na2O8 · 2H2O
Numer CAS:
Masa cząsteczkowa:
372.24
Beilstein:
3900609
Numer WE:
Kod UNSPSC:
41116107
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

agency

traceable to Ph. Eur. D2900000
traceable to USP 1233009

rodzina API

edta

Certyfikat analizy

current certificate can be downloaded

metody

HPLC: suitable
gas chromatography (GC): suitable

mp

248 °C (dec.) (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-30°C

ciąg SMILES

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

Klucz InChI

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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Opis ogólny

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Ethylenediaminetetraacetic acid disodium salt dehydrate may be used as a reference standard in validating the potential antioxidant activity and the total phenolic content of samples of seaweed extract via metal chelation technique using ferrous ion-chelating ability assay.
Ethylenediaminetetraacetic acid disodium salt dihydrate may be used as a pharmaceutical reference standard for the determination of ethylenediaminetetraacetic acid (EDTA) in pharmaceutical formulations using ion chromatography with suppressed conductimetric detection.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAA5634 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Polecane produkty

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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Piktogramy

Health hazardExclamation mark

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

Organy docelowe

Respiratory Tract

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

EDTA determination in pharmaceutical formulations and canned foods based on ion chromatography with suppressed conductimetric detection
Krokidis AA, et al.
Analytica Chimica Acta, 535(1-2), 57-63 (2005)
Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds
Wang T, et al.
Food Chemistry, 116(1), 240-248 (2009)
Sabrina Lusvarghi et al.
Nucleic acids research, 41(13), 6637-6649 (2013-05-04)
Interaction between the viral protein Rev and the RNA motifs known as Rev response elements (RREs) is required for transport of unspliced and partially spliced human immunodeficiency virus (HIV)-1 and HIV-2 RNAs from the nucleus to the cytoplasm during the
Haiyan Zhang et al.
Analytica chimica acta, 770, 140-146 (2013-03-19)
A novel method for selective determination of Cr(III) and Cr(VI) in environmental water samples was developed based on target-induced fluorescence quenching of glutathione-stabilized gold nanoclusters (GSH-Au NCs). Fluorescent GSH-Au NCs were synthesized by a one-step approach employing GSH as reducing/protecting
Akeisha N Sanders et al.
Microbiology (Reading, England), 159(Pt 9), 1842-1852 (2013-07-09)
Escherichia coli has five genes encoding L,D-transpeptidases (Ldt) with varied functions. Three of these enzymes (YbiS, ErfK, YcfS) have been shown to cross-link Braun's lipoprotein to the peptidoglycan (PG), while the other two (YnhG, YcbB) form direct meso-diaminopimelate (DAP-DAP, or

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