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Merck

PHR1019

Supelco

Benzyl alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

Benzenemethanol

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About This Item

Wzór liniowy:
C6H5CH2OH
Numer CAS:
Masa cząsteczkowa:
108.14
Beilstein:
878307
Numer WE:
Numer MDL:
Kod UNSPSC:
12352104
eCl@ss:
39023110
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

agency

traceable to Ph. Eur. Y0000167
traceable to USP 1061901

gęstość pary

3.7 (vs air)

ciśnienie pary

13.3 mmHg ( 100 °C)
3.75 mmHg ( 77 °C)

rodzina API

benzalkonium chloride

Certyfikat analizy

current certificate can be downloaded

temp. samozapłonu

817 °F

okres trwałości

~3 yr

metody

HPLC: suitable
gas chromatography (GC): suitable

współczynnik refrakcji

n20/D 1.539 (lit.)

bp

203-205 °C (lit.)

mp

−16-−13 °C (lit.)

gęstość

1.045 g/mL at 25 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-30°C

ciąg SMILES

OCc1ccccc1

InChI

1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2

Klucz InChI

WVDDGKGOMKODPV-UHFFFAOYSA-N

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Opis ogólny

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzyl alcohol is used as a preservative in pharmaceutical preparations in concentration up to 2% and as a solubilizer in concentrations of 5%. It is effective against gram-positive organisms.

Zastosowanie

Benzyl alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC1678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Polecane produkty

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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Piktogramy

Exclamation mark

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

213.8 °F - DIN 51758

Temperatura zapłonu (°C)

101 °C - DIN 51758


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Klienci oglądali również te produkty

Simultaneous determination of bifonazole and benzyl alcohol in pharmaceutical formulations by reverse-phase HPLC.
Cudina OA, et al.
Chromatographia, 61(7-8), 415-418 (2005)
Full spectrum and selected spectrum based multivariate calibration methods for simultaneous determination of betamethasone dipropionate, clotrimazole and benzyl alcohol: Development, validation and application on commercial dosage form.
Darwish HW, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 169, 50-57 (2016)
Simultaneous spectrophotometric determination of benzyl alcohol and diclofenac in pharmaceuticals using methods based on the first derivative of the optical density ratio.
Ghasemi J, et al.
Pharmaceutical Chemistry Journal, 39(12) (2005)
Simultaneous spectrophotometric determination of piroxicam and benzyl alcohol in gel forms.
Goger NG, et al.
Chem. Anal. (Warsaw), 50(6), 1059-1059 (2005)
C L Froebe et al.
Dermatologica, 181(4), 277-283 (1990-01-01)
The relationship between the in vivo irritation potential of sodium lauryl sulfate (SLS) and linear alkyl benzene sulfonate (LAS) and the ability of these two surfactants to remove lipid from the stratum corneum (SC) in vitro were investigated. Either surfactant

Protokoły

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

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