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Merck
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安全性情報

V8379

Sigma-Aldrich

Human Vitronectin

from human plasma, powder, suitable for cell culture

別名:

血清拡散因子

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About This Item

CAS番号:
MDL番号:
UNSPSCコード:
12352202
NACRES:
NA.75

製品名

ビトロネクチン ヒト血漿由来, lyophilized powder, BioReagent, suitable for cell culture

由来生物

human plasma

品質水準

製品種目

BioReagent

フォーム

lyophilized powder

分子量

A subunit 75 kDa
B subunit 65 kDa

包装

pkg of 50 μg

テクニック

cell culture | mammalian: suitable

表面被覆率

0.1 μg/cm2

溶解性

water: soluble 0.050 mg/mL, clear, colorless

UniProtアクセッション番号

輸送温度

ambient

保管温度

2-8°C

遺伝子情報

human ... VTN(7448)

アプリケーション

細胞培養基層としては 0.1 μg/cm2での使用が推奨されます。接着の最適条件は細胞の種類や用途によって異なります。

生物化学的/生理学的作用

Vitronectin binds to glycosaminoglycans, is incorporated as an inhibitor to the membrane cytolytic attack complex of the complement system, has interaction with thrombin and antithrombin III during coagulation, and may play a role in the coagulation pathway.

構成

ビトロネクチンと結合するインテグリン受容体を有する細胞には、血小板、内皮細胞、メラノ-マ細胞、骨肉腫などがあります。

注意

The lyophilized product should be stored desiccated at 2-8°C. Under these conditions it is stable for at least 2 years. Aliquots should be stored at -20°C or -70°C, but repeated freezing and thawing should be avoided.

調製ノート

水溶性(1 mL/vial)

免責事項

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

V8379-500UG:
V8379-VAR:
V8379-BULK:
V8379-50UG:
V8379-50UG-PW:


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Theodora Chatzisideri et al.
Journal of medicinal chemistry, 65(1), 271-284 (2021-12-31)
c(RGDyK)-based conjugates of gemcitabine (GEM) with the carbonate and carbamate linkages in the 6-OH group of GEM were synthesized for the targeted delivery of GEM to integrin αvβ3, overexpressing cancer cells to increase the stability as well as the tumor
The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.
Margheri F, Luciani C, Taddei ML, et al.
Oncotarget, 5(6), 1538-1553 (2014)
Francesca Posa et al.
Biomaterials, 267, 120484-120484 (2020-11-04)
Here we present the use of surface nanopatterning of covalently immobilized BMP-2 and integrin selective ligands to determine the specificity of their interactions in regulating cell adhesion and focal adhesion assembly. Gold nanoparticle arrays carrying single BMP-2 dimers are prepared
Lorenzo Sernissi et al.
Bioorganic & medicinal chemistry, 24(4), 703-711 (2016-01-13)
4-Amino- and 5-amino-cyclopropane pipecolic acids (CPAs) with cis relative stereochemistry between the carboxylic and amino groups were used as templates to prepare cyclic peptidomimetics containing the RGD sequence as possible integrin binders. The peptidomimetic c(RGD8) built on the 5-amino-CPA displayed
Ta-Chun Kao et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 102(3), 463-476 (2013-09-17)
Cancer-initiating cells [cancer stem cells (CSCs)] in colon cancer cells can be selectively suppressed when they are cultured on Pluronic (nanosegment)-grafted dishes, whereas CSCs are maintained on conventional tissue culture dishes and extracellular matrix-coated dishes. CSCs persist in tumors as

資料

3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models

3D cell culture overview: 3D cell cultures are increasingly being used for basic research and drug discovery. Learn about 2D vs 3D cell culture, advantage of 3D cell culture, and what about the techniques available to develop your 3D cell model.

Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.

Extracellular matrix proteins such as laminin, collagen, and fibronectin can be used as cell attachment substrates in cell culture.

すべて表示

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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